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Comfortable Wireless Mouse

If you're a heavy computer user, you'll want a mouse that's comfortable as well as easy to use. And if you're a gamer, you'll want one that's responsive and accurate. The best mice for most people offer multiple buttons and adjustable sensitivity. They're also designed to be comfortable in your hand and to prevent hand cramps or pain when used for long periods. Browse the top-ranked list of comfortable wireless mice below along with associated reviews and opinions.   

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  1. Logitech - M310 Wireless Optical Ambidextrous Mouse - Wireless - Peacock Blue

    SKU: J7H7ZLVLQJ

    Product Description

    An ergonomic, ambidextrous wireless mouse in peacock blue with soft rubber grips and smooth tracking.
    See all Mice
    Your price for this item is $17.99
    Save $5
    The previous price was $22.99

  2. Logitech - M325s Wireless Optical Compact Ambidextrous Mouse - Wireless - Black

    SKU: J7H7ZYGV6J

    Product Description

    A wireless black compact mouse featuring ambidextrous design, micro-precise scrolling, and up to 18 months' battery life.
    See all Mice
    Your price for this item is $11.50
    Save $11
    The previous price was $22.99

  3. Logitech - M317 Wireless Optical Mouse - Wireless - Blue

    SKU: J7H7ZY7YLJ

    Product Description

    A compact blue wireless mouse featuring a contoured design, soft rubber grips, and ambidextrous comfort.
    See all Wireless & Bluetooth Mice
    Your price for this item is $17.99
    Save $5
    The previous price was $22.99

  4. Logitech - M317 Wireless Optical Mouse - Wireless - Black

    SKU: J7H7ZY742Z

    Product Description

    A compact black wireless mouse featuring a contoured design, soft rubber grips, and plug-and-play convenience.
    See all Wireless & Bluetooth Mice
    Your price for this item is $17.99
    Save $5
    The previous price was $22.99

  5. Logitech - Wave Keys MK670 Combo Ergonomic Wireless Membrane Keyboard and Mouse Bundle for PC/Mac with Integrated Palm-rest - Graphite

    SKU: J7H7ZYG894

    Product Description

    An ergonomic wireless keyboard and mouse combo in graphite with cushioned palm rest and contoured grip.
    See all Keyboard & Mouse Combos
    Your price for this item is $79.99
    Save $10
    The previous price was $89.99

  6. Logitech - M240 Silent Bluetooth Wireless Optical Ambidextrous Mouse - Wireless - Rose

    SKU: J7H7ZYG7LP

    Product Description

    A quiet, ambidextrous Bluetooth mouse in rose with wireless connectivity and 18-month battery life.
    See all Mice
    Your price for this item is $11.50
    Save $11
    The previous price was $22.99

  7. Logitech - M240 Silent Bluetooth Wireless Optical Ambidextrous Mouse - Wireless - Off-White

    SKU: J7H7ZYG7G3

    Product Description

    An ultra-quiet, ambidextrous off-white Bluetooth mouse with wireless connectivity and 18-month battery life.
    See all Mice
    Your price for this item is $11.50
    Save $11
    The previous price was $22.99

  8. CORSAIR - IRONCLAW WIRELESS SE FPS/MOBA/MMO Gaming Mouse - Wireless - Black

    SKU: J39TSCHV4H

    Product Description

    A black wireless gaming mouse featuring a 26k DPI sensor, tri-mode connectivity, and textured grips.
    See all Gaming Mice
    Your price for this item is $89.99

  9. Pulsar - X2H Mini Wireless Gaming Mouse - Wireless - Superclear

    SKU: BGWYZZGHL2

    Product Description

    A wireless gaming mouse with a translucent black shell, red accents, and a lightweight, comfortable grip.
    See all Gaming Mice
    Your price for this item is $69.99
    Save $30
    The previous price was $99.99

  10. Incase - Wireless Desktop 900 EN Layout Designed by Microsoft - Black

    SKU: JX8R8CT22W

    Product Description

    A sleek black wireless keyboard and mouse set featuring quiet-touch keys, dual-handed design, and encrypted connectivity.
    See all Wireless & Bluetooth Keyboards
    Your price for this item is $50.99
    Save $9
    The previous price was $59.99
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In-store pricing may vary. Prices and offers are subject to change. © 2026 Best Buy. All rights reserved. BEST BUY, the BEST BUY logo, the tag design, and MY BEST BUY are trademarks of Best Buy and its affiliated companies.