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Comfortable Mouse

The best mouse for you is the one that fits your hand, works with your computer, and feels good to use. If you spend a lot of time on the computer, choosing the right mouse can have a big impact on your comfort and productivity. Browse the top-ranked list of comfortable mice below along with associated reviews and opinions.  

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  1. Logitech - Lift for Mac Wireless Bluetooth Optical Ergonomic Mouse with 4 Customizable Buttons - Wireless - Off-White

    SKU: J7H7ZY3FQH

    Product Description

    An ergonomic off-white Bluetooth mouse with quiet clicks, four customizable buttons, and a vertical design for comfort.
    See all Mice
    Your price for this item is $81.99

  2. Logitech - ERGO M575 S Wireless Ergonomic Trackball Mouse - Wireless - White

    SKU: J7H7ZY8FZJ

    Excellent mouse, I got it for a friend who's on the PC all day at work, he told me it works great, links up fast to other Logitech devices, and its very comfortable....The wireless feature is handy....

    Product Description

    An ergonomic white wireless trackball mouse offering thumb control, Bluetooth connectivity, and reduced forearm strain.
    See all Mice
    Your price for this item is $44.99
    Save $5
    The previous price was $49.99

  3. Logitech - Signature M650 for Business Wireless Optical Mouse For Small to Medium Sized Hands - Wireless - Graphite

    SKU: J7H7ZY3WWQ

    Product Description

    A graphite wireless mouse with SilentTouch technology, SmartWheel precision, and secure Bluetooth or USB connectivity.
    See all Wireless & Bluetooth Mice
    Your price for this item is $37.99
    Save $2
    The previous price was $39.99

  4. J-Tech Digital - Wireless Ergonomic Mouse with Adjustable DPI, Side Thumb Scroll Wheel, and Comfortable Palm Rest - Wireless - Black

    SKU: J3GW77ZFWX

    Product Description

    A wireless black ergonomic mouse featuring adjustable DPI, side thumb scroll wheel, and a comfortable palm rest.
    See all Wireless & Bluetooth Mice
    Your price for this item is $27.99

  5. Adesso - iMouse E30 Wireless Vertical Ergonomic Right-Handed Mouse, 6 Buttons, 4800 DPI - Wireless - Black

    SKU: J32P877SWK

    Product Description

    A wireless, ergonomic right-handed mouse in black with six buttons and up to 2400 DPI sensitivity.
    See all Wireless & Bluetooth Mice
    Your price for this item is $54.61
    Save $2
    The previous price was $56.69

  6. CHERRY - MW 8C Ergo Wireless Optical Mouse - Black

    SKU: J39HYZ7KQL

    Product Description

    An ergonomic black wireless mouse featuring anodized aluminum buttons, Bluetooth connectivity, and a comfortable thumb rest.
    See all Wireless & Bluetooth Mice
    Your price for this item is $71.74

  7. Logitech - MK235 Wireless Membrane Keyboard and Optical Mouse Bundle for PC - Black

    SKU: J7H7ZYCTGG

    Product Description

    A durable black wireless keyboard and mouse combo featuring spill resistance, plug-and-play setup, and long battery life.
    See all Keyboard & Mouse Combos
    Your price for this item is $24.99
    Save $3
    The previous price was $27.99

  8. CORSAIR - IRONCLAW WIRELESS SE FPS/MOBA/MMO Optical Gaming Mouse - Wireless - Black

    SKU: J39TSCHV4H

    Product Description

    A black wireless gaming mouse featuring a 26k DPI sensor, tri-mode connectivity, and textured grips.
    See all Gaming Mice
    Your price for this item is $89.99

  9. Pulsar - X2H Mini Wireless Gaming Mouse - Wireless - Superclear

    SKU: BGWYZZGHL2

    Product Description

    A wireless gaming mouse with a translucent black shell, red accents, and a lightweight, comfortable grip.
    See all Gaming Mice
    Your price for this item is $99.99

  10. Pulsar - X2H Mini Wireless Gaming Mouse - Wireless - Clear Black

    SKU: BGWYZZGHLT

    Product Description

    A lightweight wireless gaming mouse featuring a translucent clear black shell with striking red accents.
    See all Gaming Mice
    Your price for this item is $99.99
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In-store pricing may vary. Prices and offers are subject to change. © 2026 Best Buy. All rights reserved. BEST BUY, the BEST BUY logo, the tag design, and MY BEST BUY are trademarks of Best Buy and its affiliated companies.