A:Answer Nest Thermostat E works with 85% of 24V heating and cooling systems, including gas, electric, forced air, heat pump, radiant, oil, hot water, solar and geothermal. Nest Thermostat E can replace your 4-wire thermostat if your system is Nest-compatible. You can take a look at this article to determine if yoursystem is compatible with Nest Thermostat E : https://support.google.com/googlenest/answer/9246656
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