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I own a XFX RX-580P8DBRR and the XFX RX-480P8DFA6. My pc is a dual boot win8.1Pro64bit/ Win10Pro64bit. I have installed both cards and they ran crossfire mode no problem. Naturally my rx-580 dialed back its speed to match the slower rx-480, but that is by design. AMD crossfire operates through the drivers for the card/pci-e slots.
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