A:Answer Yes, this lens will work on a Rebel T6 which has a crop sensor. I have a Canon Mark 3 which is a full frame sensor. So a 100mm lens will be 100mm. With any crop sensor body, you need to multiply 1.6 by the lens you are looking to buy. So for your T6, a 100mm lens will actually act like 160mm lens.
You can't go wrong buying this lens, it's Amazing! And so sharp! You can use it for macro or portrait photography. I highly recommend this lens.