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From googling "2008 Mac Pro" and clicking on the link that takes one to the Apple support website we learn that we have: "Double-wide, 16-lane PCI Express 2.0 graphics slot with..." and "Three open full-length PCI Express expansion slots [One PCI Express 2.0 x16 slot, Two PCI Express x4 slots]". From googling "NVIDIA GeForce 7300 GT" and clicking on the link that takes one to techpowerup's GPU database, we see that the card we are wanting to replace has three outputs (DVI, VGA, S-Video) and supports DirectX 9 and OpenGL 2.1. We also see the performance specs as well. Then, googling "nvidia GeForce GTX 760" and again clicking on the link that takes one to techpowerup's GPU database, we see that the card we are considering has as outputs: 2 x DVI, 1 x HDMI, and 1 x DisplayPort. So we are losing VGA and S-Video connectivity, but gaining HDMI and DisplayPort. Is that relevant in your particular situation? We also see that the card supports DirectX 12 and OpenGL 4.6 which helps with meeting minimum requirements of newer software. We also see that the performance of this card very brightly outshines the performance of the card we are replacing. So now we need to consider the power requirements of the card versus the power available. This candidate card has a TDP of 170 Watts. Returning to the Apple support website we see that 300 Watts is available, which is good. But then we notice that this card we are considering is expecting a PCIe 3.0 bus and the Mac Pro has a PCIe 2.0 bus. Can a PCIe 3.0 card be used in a PCIe 2.0 machine? I don't know the answer, but I bet it can be found with Google.
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