A:Answer The differences in the two systems is actually apparent when you've tried both out. For one, the CT380 soundbar is 5" shorter, thus suited for a 40"+ TV while the CT780, being longer, is suited best for 46"+ systems. The finishes are slightly different on the back portion, the CT380 has a fake leather looking cover, while the CT780 has a sleek piano black finish in the back, the covers on the front is the same on both. Finally, I had both systems connected at one time and to me the level of sound and quality on the CT780 is excellent while the CT380 is good. I consider myself an audiophile and I was going to purchase a far more expensive product but the CT780 hits the price and sound quality sweet spot. And if you are worried about the extra $100, find an open box online at Bestbuy.com, you'll save a ton of money that way. Good luck!