A:Answer My windows 10 detects these as SATA if SATA and as a hard drive and gives it a drive letter. Would you be able to install games? Sure, but i doubt it is going to run as quickly as internally installed drive. So, if you are looking for space to install and run games then yes, but too much HDD transferring back and forth might not give you the performance you're looking for. Then again, are you looking for just booting the game seems like it'd work well. Make sure you've got USB 3.0 so you get the fastest transfer rates.