
Full Panoramic Visual and Audio Experience: Ultra-wide 21:9 2560 x 1080 resolution AH-IPS Cinematic Monitor

Q: Can you run two different pcs on this at the same time?
A: No, you cannot run two different PCs on this monitor at the same time. It does not have a multi display feature.
Q: Does this have a built in microphone as well?
A: Nope, only speakers.
A: The question is not so much compatibility but rather if you'll get the full benefit of the monitor. That would depend on the resolution that your graphics card can do. Another issue to consider is the video out on your desktop. The monitor has HDMI as well as DVI connections so you should be fine in that sense.