A:Answer You can use these Samsung M.2 drives in a PCIE slot BUT only if you buy a separate PCIE M.2 adapter. It is a 4x card that plugs into the PCIE slot with a M.2 socket mount. You would insert the Samsung drive onto the card and then install the card into the PCIE slot. These adapters are not expensive, usually between $15 and $30. Newer motherboards have M.2 slots on the boards by default and don't require the adapters, but older boards need them to work.
