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Ergonomic Wireless Laser Mouse

An ergonomic mouse is a mouse that has been designed to reduce the amount of stress that your hand experiences while using it. Ergonomic mice are designed to fit comfortably in your hand, and they often have features that make them more comfortable to use. Browse the top-ranked list of ergonomic wireless laser mice below along with associated reviews and opinions. 

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  1. Logitech - Lift Vertical Wireless Optical Ergonomic Mouse with 4 Customizable Buttons - Wireless - Graphite

    SKU: J7H7ZY3F9C

    Product Description

    An ergonomic graphite wireless mouse with quiet clicks, 4 customizable buttons, and a comfortable vertical design.
    See all Mice
    Your price for this item is $69.99
    Save $10
    The previous price was $79.99

  2. JLab - JBuds Ergonomic Wireless Mouse - Wireless - Black

    SKU: J3GW8XZ6LZ

    JLab - JBuds Ergonomic Wireless Mouse - Black...Excellent Ergonomic Mouse...To me this JBuds Ergonomic Wireless Mouse is great. I have not experience any of the pain in my wrist that I was experiencing...

    Product Description

    An ergonomic black wireless mouse featuring seven programmable buttons, Bluetooth connectivity, and a contoured vertical design.
    See all Mice
    Your price for this item is $33.99
    Save $6
    The previous price was $39.99

  3. Logitech - ERGO M575 S Wireless Ergonomic Trackball Mouse - Wireless - White

    SKU: J7H7ZY8FZJ

    Ergonomic mouse...The wireless feature is handy. It is more comfortable than other mice. ...I have used the Logitech wireless ergonomic Trackball Mouse for years...I have another computer and it has its...

    Product Description

    An ergonomic white wireless trackball mouse offering thumb control, Bluetooth connectivity, and reduced forearm strain.
    See all Mice
    Your price for this item is $39.99
    Save $10
    The previous price was $49.99

  4. Logitech - MX Master 4 - Adobe Edition - Wireless Laser Ergonomic Mouse with Advanced Performance Haptic Feedback - Wireless - Black

    SKU: J7H7ZYLGXY

    ***PROS***+ Out of the box, the Master 4 mimics the silhouette of the Master series as a whole, exemplifying the ergonomic- and productivity-focused design seen its predecessors.

    Product Description

    An ergonomic black wireless mouse featuring advanced haptic feedback, 8 programmable buttons, and USB-C charging.
    See all Wireless & Bluetooth Mice
    Your price for this item is $119.99

  5. Logitech - MX Master 4 Wireless Laser Ergonomic Mouse with Advanced Performance Haptic Feedback - Wireless - Pale Gray

    SKU: J7H7ZYLG2X

    Product Description

    An ergonomic pale gray wireless mouse featuring advanced haptic feedback, 8 programmable buttons, and USB-C charging.
    See all Wireless & Bluetooth Mice
    Your price for this item is $119.99

  6. Keychron - M6 Ergonomic Wired & Wireless Laser Mouse w/ Macro Button & Fast-Scrolling Metal Wheel, For Windows PC & Mac - Wired - Black

    SKU: CGJVZ4YC3G

    Product Description

    An ergonomic black wireless mouse featuring Bluetooth, wired options, and over ten programmable macro buttons.
    See all Wireless & Bluetooth Mice
    Your price for this item is $42.49
    Save $7
    The previous price was $49.99

  7. Incase - Bluetooth Ergonomic Mouse Designed by Microsoft - Wireless - Black

    SKU: JX8R8CHFLT

    Product Description

    An ergonomic black wireless mouse offering Bluetooth connectivity, precision navigation, and two programmable buttons.
    See all Mice
    Your price for this item is $38.99
    Save $21
    The previous price was $59.99

  8. Logitech - MX Master 4 for Business Wireless Bluetooth Laser Ergonomic Right-handed Mouse with Haptic Feedback and Actions Ring - Wireless - Graphite

    SKU: J7H7ZYLGXH

    Product Description

    A graphite ergonomic wireless mouse featuring haptic feedback, 8K DPI laser sensor, and customizable Actions Ring.
    See all Wireless & Bluetooth Mice
    Your price for this item is $119.99

  9. JLab - EPIC Wireless Bluetooth Mouse 2 - Wireless - Black

    SKU: J3GW8XZQQC

    Product Description

    A sleek black wireless Bluetooth mouse offering pro-level performance and customizable button profiles for any setup.
    See all Mice
    Your price for this item is $59.99

  10. Logitech - ERGO M575 Wireless Trackball Ergonomic Mouse for Business - Wireless - Graphite

    SKU: J7H7ZY3TKS

    Product Description

    An ergonomic graphite wireless trackball mouse with smooth thumb control, customizable buttons, and quiet clicks.
    See all Wireless & Bluetooth Mice
    Your price for this item is $49.99
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In-store pricing may vary. Prices and offers are subject to change. © 2026 Best Buy. All rights reserved. BEST BUY, the BEST BUY logo, the tag design, and MY BEST BUY are trademarks of Best Buy and its affiliated companies.