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Large Ergonomic Mouse

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Best Buy customers often prefer the following products when searching for Large Ergonomic Mouse.

If you're a gamer, a designer, or just someone who spends a lot of time on the computer, you know the importance of a comfortable mouse. You want one that fits your hand well and is easy on the wrists. You also want one that has buttons in the right places so it's easy to move your character around on the screen. Browse the top-ranked list of large ergonomic mice below along with associated reviews and opinions.

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  1. Apple - Magic Trackpad - Multi-Touch Surface (USB-C) - Wireless - White Multi-Touch Surface - Front_Zoom
    Top comment

    "Ergonomic and fast...Nice, fast easy to use and ergonomic. Customer service was great...Very ergonomic to use, takes time to get used to the hand movement"

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    Product Description

    Magic Trackpad is wireless and rechargeable, and it includes the full range of Multi-Touch gestures and Force Touch technology. Sensors underneath the trackpad surface detect subtle differences in the amount of pressure you apply, bringing more functionality to your fingertips and enabling a deeper connection to your content. It features a large edge-to-edge glass surface area, making scrolling and swiping through your favorite content more productive and comfortable than ever. Magic Trackpad pairs automatically with your Mac, so you can get to work right away. The rechargeable battery will power it for about a month or more between charges. It includes a woven USB‑C Charge Cable that lets you pair and charge by connecting to a USB‑C port on your Mac. Magic Trackpad works seamlessly with Apple Vision Pro for activities like arranging apps in 3D space or navigating complex spreadsheets.
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    Top comment

    "Ergonomic and fast...Nice, fast easy to use and ergonomic. Customer service was great...Very ergonomic to use, takes time to get used to the hand movement"

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    Product Description

    Magic Trackpad is wireless and rechargeable, and it includes the full range of Multi-Touch gestures and Force Touch technology. Sensors underneath the trackpad surface detect subtle differences in the amount of pressure you apply, bringing more functionality to your fingertips and enabling a deeper connection to your content. It features a large edge-to-edge glass surface area, making scrolling and swiping through your favorite content more productive and comfortable than ever. Magic Trackpad pairs automatically with your Mac, so you can get to work right away. The rechargeable battery will power it for about a month or more between charges. It includes a woven USB‑C Charge Cable that lets you pair and charge by connecting to a USB‑C port on your Mac. Magic Trackpad works seamlessly with Apple Vision Pro for activities like arranging apps in 3D space or navigating complex spreadsheets.
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    Your price for this item is $119.99
    The comparable value price is $129.99

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  2. Glorious - Model D 2 Wired Optical RGB Gaming Mouse with 6 Programmable Buttons - Wired - Matte White - Front_Zoom
    Top comment

    "Amazing mouse...Really nice mouse if you can snag it on sale. Fits perfect for my hands and is extremely good for overall use."

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    Product Description

    The Model D 2’s supportive ultralight weight (58g) shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best.
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    Top comment

    "Amazing mouse...Really nice mouse if you can snag it on sale. Fits perfect for my hands and is extremely good for overall use."

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    Product Description

    The Model D 2’s supportive ultralight weight (58g) shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best.
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    Your price for this item is $44.99
    The comparable value price is $64.99

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  3. Glorious - Model D 2 Wireless Optical RGB Gaming Mouse with 6 Programmable Buttons - Wireless - Matte White - Front_Zoom
    Top comment

    "Amazing mouse its an amazing step up from my last mouse its completely worth the price...Smooth mouse...Great Mouse glides across my mousepad pad smooth great feel i live the drag clicking cool RGB and great feel on the hand"

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    Product Description

    For gamers who want the agility of a symmetrical mouse, but value the added supportive comfort of an ergonomic shape. The Model D 2’s supportive shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best. The Model D 2 Wireless lets users connect via lag-free 2.4 GHz wireless or versatile Bluetooth depending on their needs – a feature not all of its competitors share.
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    Top comment

    "Amazing mouse its an amazing step up from my last mouse its completely worth the price...Smooth mouse...Great Mouse glides across my mousepad pad smooth great feel i live the drag clicking cool RGB and great feel on the hand"

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    Product Description

    For gamers who want the agility of a symmetrical mouse, but value the added supportive comfort of an ergonomic shape. The Model D 2’s supportive shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best. The Model D 2 Wireless lets users connect via lag-free 2.4 GHz wireless or versatile Bluetooth depending on their needs – a feature not all of its competitors share.
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    Your price for this item is $74.99
    The comparable value price is $99.99

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  4. Turtle Beach - Pure SEL Ultra-Light Wired Ergonomic RGB Gaming Mouse with 8K DPI Optical Sensor & Mechanical Switches - Wired - White - Front_Zoom
    Top comment

    "Perfect mouse...Overall, for the price, this mouse punches way above its weight. If you're looking for a reliable, no-nonsense gaming mouse that’s also lightweight and durable, the Turtle Beach Pure SEL is a great choice....Best Buy sent wrong color mouse...I ordered a white mouse but got a black one instead. It looks like the mice got mislabeled stickers indicating white mouse when the box image and content is a black mouse. "

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    Product Description

    Pure Performance. The Turtle Beach Pure SEL Gaming Mouse leverages over a decade of Kone’s ergonomic engineering into a 49g ultra lightweight design allowing for quick flick shots and large mouse swipes helping you hit your targets faster than ever. Enjoy crisp tactile performance with mechanical switches that are rated for 20 million click durability, precisely pre-tensioned with leaf-springs improving reliability and response time to deliver the most accurate satisfying click ever. The PixArt 8K DPI sensor provides precise tracking and 200 IPS tracking speed in combination with the pure PTFE glides giving you the fastest and smoothest experience possible. Pure SEL is designed to shine with a stylish semi-translucent shell with a fully customizable RGB projection of the Turtle Beach logo onto the back of the mouse and AIMO intelligent lighting compatibility.
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    Top comment

    "Perfect mouse...Overall, for the price, this mouse punches way above its weight. If you're looking for a reliable, no-nonsense gaming mouse that’s also lightweight and durable, the Turtle Beach Pure SEL is a great choice....Best Buy sent wrong color mouse...I ordered a white mouse but got a black one instead. It looks like the mice got mislabeled stickers indicating white mouse when the box image and content is a black mouse. "

    See all customer reviews

    Product Description

    Pure Performance. The Turtle Beach Pure SEL Gaming Mouse leverages over a decade of Kone’s ergonomic engineering into a 49g ultra lightweight design allowing for quick flick shots and large mouse swipes helping you hit your targets faster than ever. Enjoy crisp tactile performance with mechanical switches that are rated for 20 million click durability, precisely pre-tensioned with leaf-springs improving reliability and response time to deliver the most accurate satisfying click ever. The PixArt 8K DPI sensor provides precise tracking and 200 IPS tracking speed in combination with the pure PTFE glides giving you the fastest and smoothest experience possible. Pure SEL is designed to shine with a stylish semi-translucent shell with a fully customizable RGB projection of the Turtle Beach logo onto the back of the mouse and AIMO intelligent lighting compatibility.
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    Your price for this item is $23.99
    Clearance
    The comparable value price is $39.99

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  5. Glorious - Model D 2 Wired Optical RGB Gaming Mouse with 6 Programmable Buttons - Wired - Matte Black - Front_Zoom
    Top comment

    "Gaming mouse...Awsome mouse felt like it was made for my hand looks cool too..."A Gaming Mouse That Combines Precision and Comfor...Overall, it’s a fantastic mouse that balances aesthetics, functionality, and value. "

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    Product Description

    The Model D 2’s supportive ultralight weight (58g) shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best.
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    Top comment

    "Gaming mouse...Awsome mouse felt like it was made for my hand looks cool too..."A Gaming Mouse That Combines Precision and Comfor...Overall, it’s a fantastic mouse that balances aesthetics, functionality, and value. "

    See all customer reviews

    Product Description

    The Model D 2’s supportive ultralight weight (58g) shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best.
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    Your price for this item is $49.99
    The comparable value price is $64.99

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  6. Turtle Beach - Pure SEL Ultra-Light Wired Ergonomic RGB Gaming Mouse with 8K DPI Optical Sensor & Mechanical Switches - Wired - Black - Front_Zoom
    Top comment

    "super ergonomic to use and feels good, doesn’t start to stick once you use it a lot, pretty good quality for the price...[This review was collected as part of a promotion.] This mouse is incredibly lightweight and responsive—perfect for both casual use and gaming. "

    See all customer reviews

    Product Description

    Pure Performance. The Turtle Beach Pure SEL Gaming Mouse leverages over a decade of Kone’s ergonomic engineering into a 49g ultra lightweight design allowing for quick flick shots and large mouse swipes helping you hit your targets faster than ever. Enjoy crisp tactile performance with mechanical switches that are rated for 20 million click durability, precisely pre-tensioned with leaf-springs improving reliability and response time to deliver the most accurate satisfying click ever. The PixArt 8K DPI sensor provides precise tracking and 200 IPS tracking speed in combination with the pure PTFE glides giving you the fastest and smoothest experience possible. Pure SEL is designed to shine with a stylish semi-translucent shell with a fully customizable RGB projection of the Turtle Beach logo onto the back of the mouse and AIMO intelligent lighting compatibility.
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    Top comment

    "super ergonomic to use and feels good, doesn’t start to stick once you use it a lot, pretty good quality for the price...[This review was collected as part of a promotion.] This mouse is incredibly lightweight and responsive—perfect for both casual use and gaming. "

    See all customer reviews

    Product Description

    Pure Performance. The Turtle Beach Pure SEL Gaming Mouse leverages over a decade of Kone’s ergonomic engineering into a 49g ultra lightweight design allowing for quick flick shots and large mouse swipes helping you hit your targets faster than ever. Enjoy crisp tactile performance with mechanical switches that are rated for 20 million click durability, precisely pre-tensioned with leaf-springs improving reliability and response time to deliver the most accurate satisfying click ever. The PixArt 8K DPI sensor provides precise tracking and 200 IPS tracking speed in combination with the pure PTFE glides giving you the fastest and smoothest experience possible. Pure SEL is designed to shine with a stylish semi-translucent shell with a fully customizable RGB projection of the Turtle Beach logo onto the back of the mouse and AIMO intelligent lighting compatibility.
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    Your price for this item is $19.99
    The comparable value price is $39.99

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  7. Glorious - Model D 2 Wireless Optical RGB Gaming Mouse with 6 Programmable Buttons - Wireless - Matte Black - Front_Zoom
    Top comment

    "Lightweight mouse that feels great...It has a nice curved shape which makes it more ergonomic and is very light weight....Great Mouse!...Lots of people don't like glorious mice. I think theyre great and super light. Had mine for 5+ years and had to upgrade."

    See all customer reviews

    Product Description

    For gamers who want the agility of a symmetrical mouse, but value the added supportive comfort of an ergonomic shape. The Model D 2’s supportive shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best. The Model D 2 Wireless lets users connect via lag-free 2.4 GHz wireless or versatile Bluetooth depending on their needs – a feature not all of its competitors share.
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    Top comment

    "Lightweight mouse that feels great...It has a nice curved shape which makes it more ergonomic and is very light weight....Great Mouse!...Lots of people don't like glorious mice. I think theyre great and super light. Had mine for 5+ years and had to upgrade."

    See all customer reviews

    Product Description

    For gamers who want the agility of a symmetrical mouse, but value the added supportive comfort of an ergonomic shape. The Model D 2’s supportive shape lets gamers with medium to large hands play with confident control and lasting comfort – especially when held in a palm or claw grip. Paired with its ergonomic shape, the Model D 2’s low weight makes aiming feel effortlessly quick and precise with less risk of fatigue during longer play sessions. Unlike its competitors, the Model D 2 does not compromise on RGB lighting to achieve lower weights, allowing gamers to both look and play at their best. The Model D 2 Wireless lets users connect via lag-free 2.4 GHz wireless or versatile Bluetooth depending on their needs – a feature not all of its competitors share.
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    Your price for this item is $74.99
    The comparable value price is $99.99

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  8. Logitech - PRO X SUPERLIGHT Lightweight Wireless Optical Gaming Mouse with HERO 25K Sensor - Wireless - White - Front_Zoom
    Top comment

    "Great mouse for gaming...Long battery life and very responsive with a cool design and good ergonomics....ultra light mouse with ergonomic grip, would reccomend for valorant"

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    Product Description

    Introducing PRO X SUPERLIGHT—one of our lightest, fastest PRO mouse ever. Powered by LIGHTSPEED, it’s here to help you remove all obstacles, so you can focus on nothing but winning. Get insanely precise, fast, and consistent control with HERO Sensor. Take first faster with zero-additive PTFE feet that deliver a dramatically smoother glide. Developed in collaboration with a large group of the world’s best esports pros, PRO X SUPERLIGHT features hyper-minimal design, but is packed with our latest technologies and advancements. PRO X SUPERLIGHT is available in black and white.
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    Top comment

    "Great mouse for gaming...Long battery life and very responsive with a cool design and good ergonomics....ultra light mouse with ergonomic grip, would reccomend for valorant"

    See all customer reviews

    Product Description

    Introducing PRO X SUPERLIGHT—one of our lightest, fastest PRO mouse ever. Powered by LIGHTSPEED, it’s here to help you remove all obstacles, so you can focus on nothing but winning. Get insanely precise, fast, and consistent control with HERO Sensor. Take first faster with zero-additive PTFE feet that deliver a dramatically smoother glide. Developed in collaboration with a large group of the world’s best esports pros, PRO X SUPERLIGHT features hyper-minimal design, but is packed with our latest technologies and advancements. PRO X SUPERLIGHT is available in black and white.
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    Your price for this item is $89.99
    The comparable value price is $149.99

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  9. Logitech - MX ERGO S PLUS Wireless Ergonomic Trackball Mouse with 6 Programmable Buttons - Wireless - Graphite - Front_Zoom
    Top comment

    "Ergonomic Mouse...This is one of the best ergonomic mice I’ve ever owned. The extra tilt makes it incredibly comfortable for extended use."

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    Product Description

    The MX Ergo S Plus is Logitech’s most advanced ergonomic trackball mouse yet, with a 20-degree tilt angle and a 10-degree detachable wedge, and precise thumb control - user-tested and certified by United States Ergonomics. The MX Ergo S wireless ergonomic mouse is sculpted to fit the palm of your hand while keeping it relaxed, and it tilts 20 to 30 degrees for 27% less muscle activity in the forearm, providing elevated comfort throughout your day. Work faster with 6 customizable buttons and a DPI button to effortlessly switch between speed and high-precision tracking. Now with 80% quieter clicks. For even more control that's tailored to your needs, assign time-saving shortcuts and Smart Actions using the Logi Options+ App. Connect your wireless mouse to 2 devices via Bluetooth or the included Logi Bolt receiver and switch between devices with a click of the Easy-Switch button.
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    Top comment

    "Ergonomic Mouse...This is one of the best ergonomic mice I’ve ever owned. The extra tilt makes it incredibly comfortable for extended use."

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    Product Description

    The MX Ergo S Plus is Logitech’s most advanced ergonomic trackball mouse yet, with a 20-degree tilt angle and a 10-degree detachable wedge, and precise thumb control - user-tested and certified by United States Ergonomics. The MX Ergo S wireless ergonomic mouse is sculpted to fit the palm of your hand while keeping it relaxed, and it tilts 20 to 30 degrees for 27% less muscle activity in the forearm, providing elevated comfort throughout your day. Work faster with 6 customizable buttons and a DPI button to effortlessly switch between speed and high-precision tracking. Now with 80% quieter clicks. For even more control that's tailored to your needs, assign time-saving shortcuts and Smart Actions using the Logi Options+ App. Connect your wireless mouse to 2 devices via Bluetooth or the included Logi Bolt receiver and switch between devices with a click of the Easy-Switch button.
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    Your price for this item is $99.99
    The comparable value price is $119.99

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  10. Razer - DeathAdder V4 Pro Lightweight Optical Gaming Mouse with 150 Hour Battery - Wireless - White - Front_Zoom
    Top comment

    "Right handed mouse...[This review was collected as part of a promotion.] This mouse is next level for ergonomics, but I'm unsure why I was picked for this product as this is a right hand mouse and I am left handed. ...Very ergonomic, but not sure if I would have bough...Even though I am left handed it feels ergonomic, it has good tactile feedback and is very responsive. "

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    Product Description

    Become the deadliest version of yourself with the Razer DeathAdder V4 Pro—an ultra-lightweight wireless ergonomic mouse that’s the perfect esports specimen. Upgraded on all fronts with our most cutting-edge tech, feel the immediate impact as every advantage you have comes into play.
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    Top comment

    "Right handed mouse...[This review was collected as part of a promotion.] This mouse is next level for ergonomics, but I'm unsure why I was picked for this product as this is a right hand mouse and I am left handed. ...Very ergonomic, but not sure if I would have bough...Even though I am left handed it feels ergonomic, it has good tactile feedback and is very responsive. "

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    Product Description

    Become the deadliest version of yourself with the Razer DeathAdder V4 Pro—an ultra-lightweight wireless ergonomic mouse that’s the perfect esports specimen. Upgraded on all fronts with our most cutting-edge tech, feel the immediate impact as every advantage you have comes into play.
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    Your price for this item is $169.99

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