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Small Ergonomic Mouse

If you're looking for a mouse that will help you keep your petite wrists and hands healthy, consider a small ergonomic mouse. These mice are designed to fit the natural contours of your hand, reducing the stress on your joints. Not only are they comfortable to use, but they also reduce the negative effects of repetitive strain injury (RSI). Browse the top-ranked list of small ergonomic mice below along with associated reviews and opinions.

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  1. JLab - JBuds Ergonomic Wireless Mouse - Wireless - Black

    SKU: J3GW8XZ6LZ

    The best ergonomic mouse I’ve ever had. Needed a new mouse for video editing and this was the best purchase....Very nice ergonomic mouse, and works as advertised. and you can use while its charging. ...Best...

    Product Description

    An ergonomic black wireless mouse featuring seven programmable buttons, Bluetooth connectivity, and a contoured vertical design.
    See all Mice
    Your price for this item is $33.99
    Save $6
    The previous price was $39.99

  2. Logitech - Lift for Mac Wireless Bluetooth Optical Ergonomic Mouse with 4 Customizable Buttons - Wireless - Off-White

    SKU: J7H7ZY3FQH

    Product Description

    An ergonomic off-white Bluetooth mouse with quiet clicks, four customizable buttons, and a vertical design for comfort.
    See all Mice
    Your price for this item is $81.99

  3. Razer - Basilisk Mobile Optical Gaming Mouse - Wireless - Black

    SKU: J3GTVWWXY7

    The Logitech mice are either just a bit too big, or a bit too small. This mouse is right in the middle size-wise, and lighter than the Anywhere 3. ...This mouse is awesome. It’s small but it’s very ergonomic...

    Product Description

    A portable black wireless gaming mouse featuring ergonomic design, 18,000 DPI sensor, and six programmable buttons.
    See all Gaming Mice
    Your price for this item is $89.99

  4. J-Tech Digital - Vertical Wireless Ergonomic Mouse with 2.4G and Bluetooth Modes – Adjustable DPI - Wireless - White

    SKU: J3GW7747LQ

    Product Description

    A white ergonomic wireless mouse with adjustable DPI, 2.4G and Bluetooth connectivity for right-handed users.
    See all Wireless & Bluetooth Mice
    Your price for this item is $32.99

  5. Adesso - iMouse E30 Wireless Vertical Ergonomic Right-Handed Mouse, 6 Buttons, 4800 DPI - Wireless - Black

    SKU: J32P877SWK

    Product Description

    A wireless, ergonomic right-handed mouse in black with six buttons and up to 2400 DPI sensitivity.
    See all Wireless & Bluetooth Mice
    Your price for this item is $54.61
    Save $2
    The previous price was $56.69

  6. J-Tech Digital - Vertical Wireless Ergonomic Mouse - 2.4G & Bluetooth - Wireless - Black

    SKU: J3GW7747LL

    Product Description

    An ergonomic black wireless mouse with 2.4G and Bluetooth connectivity, designed to reduce wrist strain.
    See all Wireless & Bluetooth Mice
    Your price for this item is $32.99

  7. J-Tech Digital - Wireless Vertical Ergonomic Mouse - Wireless & Bluetooth - Wireless - Pink

    SKU: J3GW7747SJ

    Product Description

    A pink ergonomic wireless mouse with Bluetooth connectivity, designed for right-handed comfort and multi-device use.
    See all Wireless & Bluetooth Mice
    Your price for this item is $32.99

  8. CHERRY - MW 8C Ergo Wireless Optical Mouse - Black

    SKU: J39HYZ7KQL

    Product Description

    An ergonomic black wireless mouse featuring anodized aluminum buttons, Bluetooth connectivity, and a comfortable thumb rest.
    See all Wireless & Bluetooth Mice
    Your price for this item is $71.74

  9. Adesso - Tru-Form Media WKB-1150CB Ergonomic Wireless Membrane Optical Keyboard and Mouse - Black

    SKU: J32P8779YL

    Product Description

    An ergonomic black wireless keyboard and mouse combo featuring split-key design, palm rest, and Bluetooth connectivity.
    See all Wireless & Bluetooth Keyboards
    Your price for this item is $62.99
    Save $11
    The previous price was $74.95

  10. Verbatim - Cordless Deluxe Blue-LED Computer Mouse, Ergonomic, 8 Buttons, 2.4 GHz - Wireless - Graphite

    SKU: J72FJKJCV7

    Product Description

    An ergonomic wireless mouse in graphite with 8 buttons and Blue-LED technology for versatile surface tracking.
    See all Mice
    Your price for this item is $41.78
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In-store pricing may vary. Prices and offers are subject to change. © 2026 Best Buy. All rights reserved. BEST BUY, the BEST BUY logo, the tag design, and MY BEST BUY are trademarks of Best Buy and its affiliated companies.