A:Answer Possibly, but it might not work as expected. I tried to use one of these to replace the physical drive in a low-end Dell system, but discovered that the CPU and motherboard were not able to keep up with the drive. Before this, the computer was slow and only able to run one or two things, afterward, it MIGHT be faster at times, but generally it simply stuttered.
So the key to this working is how good the motherboard is, and whether it can handle a much much faster drive.