A:Answer No, not natively. This lens is for a mirror less APS-C sensor camera. You might be able to buy an adapter to convert an e-mount lens (this lens) to an a-mount camera (which the a390 is), but you’d be better off buying a Sony a-mount lens such as the SAL50F14, which will offer better performance and is faster to boot. It’s more expensive, but can be found cheaper. I looked around, but most adapters are a-lens to e-mount camera - as most people want such an adapter to use their lens investments on newer camera bodies, not the other way around.