A:Answer I have had a couple M510s over the years. It depends on where the USB device is plugged in. I have a steel desk with a tower computer on the floor. If I plug the USB device in the back of my computer, the mouse operation is intermittent. I used a USB extender cable to put the device at the edge of my desk and it worked flawlessly. A couple of years ago, I got a monitor arm for my display and it had USB connectors in it. I plugged the USB device into it and just walked as far as I could from the monitor (22ft) and the mouse still worked fine. So, it depends on how clear of a path the USB device has with the mouse.