A:Answer Assuming you have both a smartphone and a bluetooth-capable radio in your vehicle, you could share your WD drive (from home) via the cloud (via the provided software) and access it via the "WD My Cloud" app on your phone. Then, you could stream the music from your phone to your radio via bluetooth like you would to with Pandora.
If you meant just plugging the drive into the USB port of your car radio, I'd doubt it. Most car radios have a size limit on what size drive you can access. Buy a thumb drive instead. Plus, how would you power it?
Hope this helps :)
Mike