Best Buy customers often prefer the following products when searching for best ergonomic computer mouse.
If you spend a lot of time at your computer, an ergonomic mouse can help prevent or reduce repetitive strain injuries. These mice are designed to fit your hand more naturally, and some have other features that can help you customize how you interact with your computer. Browse the top-ranked list of best ergonomic computer mice below along with associated reviews and opinions.
Logitech - MX Vertical Advanced Wireless Optical Ergonomic Mouse with USB and Bluetooth Connection - Graphite
Model: 910-005447SKU: 6282602Top comment"Best ergonomic mouse out there. It’s lightweight and makes you forget about the difference in your grip....This is the best ergonomic mouse I have ever used....Best ergonomic mouse on the market...Best ergonomic mouse"
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MX Vertical is an advanced ergonomic mouse that combines science-driven design with the elevated performance of Logitech’s MX series. The natural handshake position of MX Vertical reduces wrist pressure and forearm strain. The unique 57° vertical angle has been optimized for an ergonomic posture without compromising a pixel of performance. MX Vertical features a 4000 DPI high-precision sensor, resulting in 4x less hand movement and reducing fatigue. And the cursor speed switch allows you to instantly adjust DPI speed and accuracy with the touch of a button. MX Vertical stays powered for up to four months on a full charge – and gets three hours of use from a one-minute quick charge.Top comment"Best ergonomic mouse out there. It’s lightweight and makes you forget about the difference in your grip....This is the best ergonomic mouse I have ever used....Best ergonomic mouse on the market...Best ergonomic mouse"
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MX Vertical is an advanced ergonomic mouse that combines science-driven design with the elevated performance of Logitech’s MX series. The natural handshake position of MX Vertical reduces wrist pressure and forearm strain. The unique 57° vertical angle has been optimized for an ergonomic posture without compromising a pixel of performance. MX Vertical features a 4000 DPI high-precision sensor, resulting in 4x less hand movement and reducing fatigue. And the cursor speed switch allows you to instantly adjust DPI speed and accuracy with the touch of a button. MX Vertical stays powered for up to four months on a full charge – and gets three hours of use from a one-minute quick charge.See all Wireless & Bluetooth MiceLogitech - ERGO M575 Wireless Trackball Mouse with Ergonomic Design - Black
Model: 910-005869SKU: 6440330Top comment"Hooray for ergonomics...I bought this ergonomic Mouse after several months of physical therapy. ...Great Ergonomic Mouse...Excellent mouse, very simple and easy to configure, excellent ergonomics, the hand fits perfectly and you can work without much effort."
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A new standard of comfort and precision. Logitech's most advanced trackball for trackball enthusiasts and consumers searching for alternatives to mice and touchpads. Delivers 20% less muscular strain compared to a regular mouse. MX ERGO PLUS features a unique adjustable hinge and extra 10° wedge for customized comfort and the latest tracking, scrolling and power management technology. Logitech FLOW enables effortless multi-computer control.Top comment"Hooray for ergonomics...I bought this ergonomic Mouse after several months of physical therapy. ...Great Ergonomic Mouse...Excellent mouse, very simple and easy to configure, excellent ergonomics, the hand fits perfectly and you can work without much effort."
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A new standard of comfort and precision. Logitech's most advanced trackball for trackball enthusiasts and consumers searching for alternatives to mice and touchpads. Delivers 20% less muscular strain compared to a regular mouse. MX ERGO PLUS features a unique adjustable hinge and extra 10° wedge for customized comfort and the latest tracking, scrolling and power management technology. Logitech FLOW enables effortless multi-computer control.See all Wireless & Bluetooth MiceLogitech - MX ERGO Plus Wireless Trackball Mouse with Ergonomic design - Graphite
Model: 910-005178SKU: 6080600Top comment"Best ergonomic trackball mouse...Best ergonomic mouse. This is must upgrade if you love trackball mouse....Best Ergonomic Mouse"
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Logitech's most advanced trackball for trackball enthusiasts and consumers searching for alternatives to mice and touchpads. Delivers 20% less muscular strain compared to a regular mouse. A unique adjustable hinge offers personalized comfort - choose the best angle for you between 0 and 20°. Precision mode button allows to instantly switch between speed and precise tracking. Easy-Switch and FLOW-enabled for effortless multi-computer workflow. Pair up to 2 computers and easily switch between them, copy and paste text, images and files. Connect using the included Logitech Unifying receiver or via Bluetooth.Top comment"Best ergonomic trackball mouse...Best ergonomic mouse. This is must upgrade if you love trackball mouse....Best Ergonomic Mouse"
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Logitech's most advanced trackball for trackball enthusiasts and consumers searching for alternatives to mice and touchpads. Delivers 20% less muscular strain compared to a regular mouse. A unique adjustable hinge offers personalized comfort - choose the best angle for you between 0 and 20°. Precision mode button allows to instantly switch between speed and precise tracking. Easy-Switch and FLOW-enabled for effortless multi-computer workflow. Pair up to 2 computers and easily switch between them, copy and paste text, images and files. Connect using the included Logitech Unifying receiver or via Bluetooth.See all Wireless & Bluetooth MiceAdesso - iMouse Wired Optical Ergonomic Mouse - Glossy black
Model: IMOUSEE1SKU: 6554094Top comment"My favorite mouse to date...I've grown to prefer ergonomic style "mice", and this is my 2nd replacing an older Anker model. ...Good ergonomic mouse...Not as good as some of the higher end programmable ergonomic mice, but definitely a good choice on a budget."
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Click in comfort with this Adesso iMouse vertical mouse. It keeps your forearm in handshake position to reduce strain, and the switchable DPI control lets you adjust the speed of navigation. This Adesso iMouse vertical mouse has two ergonomic side buttons for seamless back-and-forth browsing, and the optical sensor works on a variety of different surfaces.Top comment"My favorite mouse to date...I've grown to prefer ergonomic style "mice", and this is my 2nd replacing an older Anker model. ...Good ergonomic mouse...Not as good as some of the higher end programmable ergonomic mice, but definitely a good choice on a budget."
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Click in comfort with this Adesso iMouse vertical mouse. It keeps your forearm in handshake position to reduce strain, and the switchable DPI control lets you adjust the speed of navigation. This Adesso iMouse vertical mouse has two ergonomic side buttons for seamless back-and-forth browsing, and the optical sensor works on a variety of different surfaces.See all Ergonomic MiceLogitech - MK550 Ergonomic Full-size Wireless Keyboard and Mouse Bundle for PC - Black
Model: 920-002555SKU: 1261402Top comment"This is the best ergonomic keyboard I have ever used....The best ergonomic keyboard ever!"
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Logitech Wireless Wave Combo MK550. A mouse-and-keyboard combo that gives you a comfort curve without a learning curve. The keyboard’s Wave design with Constant Curve layout guides hands into just the right position and conforms naturally to your fingers, helping you type with ease and confidence in a familiar layout. The laser mouse is a joy to hold and use.Top comment"This is the best ergonomic keyboard I have ever used....The best ergonomic keyboard ever!"
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Logitech Wireless Wave Combo MK550. A mouse-and-keyboard combo that gives you a comfort curve without a learning curve. The keyboard’s Wave design with Constant Curve layout guides hands into just the right position and conforms naturally to your fingers, helping you type with ease and confidence in a familiar layout. The laser mouse is a joy to hold and use.See all Keyboard & Mouse CombosGlorious - Model I Wired Optical 9 Buttons Honeycomb RGB Gaming Mouse - Matte Black
Model: GLO-MS-I-MBSKU: 6519204Top comment"Best mouse company...Very comfortable and ergonomic. Lightweight and responsive....Only downside is my wrist doesnt quite rest right on the mouse but not all mice are made perfect."
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Our most feature-rich lightweight mouse yet. 9 Programmable buttons with 2 customizable magnetic thumb buttons put you in control. Looking at the highly-comfortable ergonomic shape, it's hard to believe the Model I is only 69g. Quickly adapt the Model I to your playstyle with its modular side buttons. Two of the four thumb buttons are easily-swappable for a perfect fit in your hand. Or you can use the flat shape option to completely remove their usability. Up to nine unique combinations are available for you to try out. The Model I becomes an extension of your arm for effortless control in all kinds of games. Its ergonomic body allows for a comfortable and confident grip that combats hand fatigue. Freely remap all the available buttons to your needs. Assign useful shortcuts, like instantly adjusting DPI by holding down a button, for custom control in games. Create and save up to three mouse profiles via Glorious CORE. Quickly switch between them to spend more time playing, less time tinkering.Top comment"Best mouse company...Very comfortable and ergonomic. Lightweight and responsive....Only downside is my wrist doesnt quite rest right on the mouse but not all mice are made perfect."
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Our most feature-rich lightweight mouse yet. 9 Programmable buttons with 2 customizable magnetic thumb buttons put you in control. Looking at the highly-comfortable ergonomic shape, it's hard to believe the Model I is only 69g. Quickly adapt the Model I to your playstyle with its modular side buttons. Two of the four thumb buttons are easily-swappable for a perfect fit in your hand. Or you can use the flat shape option to completely remove their usability. Up to nine unique combinations are available for you to try out. The Model I becomes an extension of your arm for effortless control in all kinds of games. Its ergonomic body allows for a comfortable and confident grip that combats hand fatigue. Freely remap all the available buttons to your needs. Assign useful shortcuts, like instantly adjusting DPI by holding down a button, for custom control in games. Create and save up to three mouse profiles via Glorious CORE. Quickly switch between them to spend more time playing, less time tinkering.See all Gaming MiceGlorious - Model D Wireless Optical Honeycomb RGB Gaming Mouse - Matte White
Model: GLO-MS-DW-MWSKU: 6519214Top comment"I was in the market for a wireless mouse. I chose this shape because I’ve always used a death adder and the ergonomic shape is similar. ...Great lightweight ergonomic gaming mouse from glorious."
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The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. Spend more time gaming with the Model D Wireless’ incredible 71* hours of play time on a single charge. (*Measured with RGB Off). D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength. Easy to clean and also helps improve airflow while you game.Top comment"I was in the market for a wireless mouse. I chose this shape because I’ve always used a death adder and the ergonomic shape is similar. ...Great lightweight ergonomic gaming mouse from glorious."
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The Model D Wireless prevents double-clicking and unresponsiveness, producing an unbelievably smooth operation. The proprietary BAMF Sensor redefines what is possible in a gaming mouse. Made in collaboration with Pixart, BAMF is optimized for unrivaled performance with a lower power draw - allowing you to game harder and longer than ever before. The sensor provides pinpoint precision with its 400 IPS tracking speed, 19,000 programmable DPI, and up to 1000 Hz polling rate. At a mere 69 grams, the Model D Wireless is light weight and utilizes a right-handed, ergonomic design that satisfyingly cradles your palm. Spend more time gaming with the Model D Wireless’ incredible 71* hours of play time on a single charge. (*Measured with RGB Off). D Wireless comes with a flexible USB-C Ascended charging cable for nonstop performance when you need it most. The mouse allows for seamless operation in wired and wireless modes. Its honeycomb shell helps reduce weight while maintaining strength. Easy to clean and also helps improve airflow while you game.See all Gaming MiceRazer Basilisk V3 X HyperSpeed Customizable Wireless Gaming Mouse - Black
Model: RZ01-04870100-R3U1SKU: 6538211Top comment"Razer nailed it again with this very responsive, light and affordable gaming mouse. Very ergonomic, feels great while using it....I'm just a bit disappointed in that it runs off AA batteries and is not rechargeable like other Razer Mice products I've bought in the past. I feel I was kind of duped into buying a cheap mouse and probably should have just bought the Corsair M65 wireless mouse as it was rechargeable and cheaper at the time."
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With the Razer Basilisk V3 X HyperSpeed, there are no limits on how you choose to play. Armed with 9 programmable controls, dual-mode wireless connectivity, and customizable Razer Chroma™ RGB, it is made to answer to only one master—you.Top comment"Razer nailed it again with this very responsive, light and affordable gaming mouse. Very ergonomic, feels great while using it....I'm just a bit disappointed in that it runs off AA batteries and is not rechargeable like other Razer Mice products I've bought in the past. I feel I was kind of duped into buying a cheap mouse and probably should have just bought the Corsair M65 wireless mouse as it was rechargeable and cheaper at the time."
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With the Razer Basilisk V3 X HyperSpeed, there are no limits on how you choose to play. Armed with 9 programmable controls, dual-mode wireless connectivity, and customizable Razer Chroma™ RGB, it is made to answer to only one master—you.See all Gaming MiceLogitech - Pebble M350 Wireless Optical Ambidextrous Mouse with Silent Click - Lavender Lemonade
Model: 910-006659SKU: 6516301Top comment"It’s convenient and cheap with minimal ergonomic design. Excelllent colorway options....Love the mouse! Not a fan of the companion keyboard. The pebble mouse isn’t the best for long days of using a mouse as it’s flag and not ergonomic like other mice you could use. "
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Own your space with Logitech Pebble M350 – a modern, slim, and silent portable mouse designed for your curated lifestyle. Make a statement with a slim mouse that can easily be scooped up and brought to the cafe or library. Silent clicking and scrolling means you can stay focused without disturbing those around you. And the Logitech Pebble stays powered for up to 18-months on a single AA battery so you don’t have to worry about losing power.Top comment"It’s convenient and cheap with minimal ergonomic design. Excelllent colorway options....Love the mouse! Not a fan of the companion keyboard. The pebble mouse isn’t the best for long days of using a mouse as it’s flag and not ergonomic like other mice you could use. "
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Own your space with Logitech Pebble M350 – a modern, slim, and silent portable mouse designed for your curated lifestyle. Make a statement with a slim mouse that can easily be scooped up and brought to the cafe or library. Silent clicking and scrolling means you can stay focused without disturbing those around you. And the Logitech Pebble stays powered for up to 18-months on a single AA battery so you don’t have to worry about losing power.See all Wireless & Bluetooth MiceGlorious - Model O Wired Optical Honeycomb RGB Gaming Mouse - Matte Black
Model: GO-BLACKSKU: 6519198Top comment"A great buy if you have medium sized hands, or don't like ergonomic mice. Truly no qualms with the mouse itself....Best gaming mouse...Tried it and it's hands down the best gaming mouse. Quality product."
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Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.Top comment"A great buy if you have medium sized hands, or don't like ergonomic mice. Truly no qualms with the mouse itself....Best gaming mouse...Tried it and it's hands down the best gaming mouse. Quality product."
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Model O’s Honeycomb Shell is the key to achieving a feather-light weight while maintaining its ultra-durable strength. You’ll barely feel the holes during gameplay, but they provide ventilation to keep your palms cool & fresh. Cleaning the Model O is easy, just use any air canister to keep your mouse good as new. Our braided cable is ultra-flexible and super lightweight, giving your mouse an almost wireless feel.See all Gaming Mice