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Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M650 L Left. The versatile mouse features an adaptive scroll SmartWheel that delivers line-by-line precision, and auto-switches to super-fast free spin mode with the flick of a finger. A choice of sizes for smaller, larger and left hands means there's a perfect fit for anyone. Seamless wireless connectivity, customizable side buttons, and a comfort shape keep you comfortably and productive hour after hour. Logitech’s SilentTouch technology delivers silent clicks to keep you focused – while the up to 24-month battery life and universal operating system compatibility ensure hassle-free performance.
Q: What is the little part called that you show with the mouse that plugs into it
A: It is a USB receiver and it is needed for the mouse to communicate via Bluetooth with your laptop /computer.

Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M650 L Left. The versatile mouse features an adaptive scroll SmartWheel that delivers line-by-line precision, and auto-switches to super-fast free spin mode with the flick of a finger. A choice of sizes for smaller, larger and left hands means there's a perfect fit for anyone. Seamless wireless connectivity, customizable side buttons, and a comfort shape keep you comfortably and productive hour after hour. Logitech’s SilentTouch technology delivers silent clicks to keep you focused – while the up to 24-month battery life and universal operating system compatibility ensure hassle-free performance.

Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M550 – featuring SmartWheel scrolling that delivers precision and speed in an instant. A choice of sizes for smaller or larger hands means there's a perfect fit for anyone. Seamless wireless connectivity, silent clicks, and a comfort shape keep you comfortable and productive hour after hour.

Upgrade to smarter scrolling, better comfort, and more productivity with the Signature M650 L. The versatile mouse features an adaptive scroll SmartWheel that delivers line-by-line precision, and auto-switches to super-fast free spin mode with the flick of a finger. A choice of sizes for smaller, larger and left hands means there's a perfect fit for anyone. Seamless wireless connectivity, customizable side buttons, and a comfort shape keep you comfortably and productive hour after hour. Logitech’s SilentTouch technology delivers silent clicks to keep you focused – while the up to 24-month battery life and universal operating system compatibility ensure hassle-free performance.

The easy-to-deploy (and manage) Signature M650 for Business Wireless Mouse improves employee productivity by 50% vs laptop touchpads. And it provides Secure Connections Only Mode—Bluetooth Low Energy Security Mode 1, Level 4 protection when paired with a Logi Bolt USB receiver. Or connect via Bluetooth Low Energy when cross-platform flexibility matters. Get line-by-line precision for documents – and super fast scrolling for long web pages by switching modes with a flick of the SmartWheel. It’s also 90% less “clicky” thanks to SilentTouch technology. In two sizes for small or large hands, and a contoured shape and soft thumb area for comfort.
| Pros for Logitech - Signature M650 L Wireless Left-Handed Scroll Mouse with Silent Clicks - Wireless - Graphite | |||
|---|---|---|---|
| There were no pros for this product— | Overall Performance, Size, Ease of Use, Connectivity, Ergonomics | Size, Overall Performance, Ease of use, Bluetooth, Silent Clicks | There were no pros for this product— |
| Cons for Logitech - Signature M650 L Wireless Left-Handed Scroll Mouse with Silent Clicks - Wireless - Graphite | |||
| There were no cons for this product— | Scroll Wheel | Scroll Wheel, Price, Side Buttons | There were no cons for this product— |
The vast majority of our reviews come from verified purchases. Reviews from customers may include My Best Buy members, employees, and Tech Insider Network members (as tagged). Select reviewers may receive discounted products, promotional considerations or entries into drawings for honest, helpful reviews.
I got this mouse for my teenage daughter who is left-handed. She is used to using the generic shaped mice with less buttons, because most of the premium options have the additional buttons on the wrong side. Now not only does she have configurable thumb buttons she can use, but a very well-designed mouse overall. - Comfortable curved shape and soft touch plastic - Quiet and smooth operation of both the scroll wheel and buttons - Easy setup: perforated packaging is easy to open; the battery is preinstalled and once I pulled the tab my computer recognized the mouse immediately (over Bluetooth) - Easily replaceable AA battery included - Multiple connection options: Bluetooth or USB wireless receiver - USB receiver can be stored in the battery compartment when not in use - 2 thumb buttons - on the correct side for left-handed users (normally forward and back, but configurable with the Logitech app) - No issues with tracking on every surface we have tried. I would definitely recommend and I might get the right-handed version for myself! The variable speed scrolling and quiet buttons would be a useful upgrade from my current mouse at work.
This review is from Logitech - Signature M650 L Wireless Left-Handed Scroll Mouse with Silent Clicks - Wireless - Graphite
Posted by MGoose
If you are left handed, with larger hands the LOGI M650 is for us. The left hand mouse allows the natural left hand thumb to access the two (2) programmable side buttons. Pairing is fast and easy with Bluetooth. No Bluetooth, the M650 comes with the standard USB transceiver for rock solid mouse operation. The feel of the embossed rubber fins is awesome. They make the mouse a pleasure especially for long periods of use. The center wheel not only serves as a center button, but smooth scrolling as well. Super accurate laser scanning over most surfaces, even glass. Happily, the single AA battery is said to last 2-years. Along with that is a true on/off switch.
This review is from Logitech - Signature M650 L Wireless Left-Handed Scroll Mouse with Silent Clicks - Wireless - Graphite
Posted by JerryZ
Review of M650 Lefthand - Large Size. The Logitech M650 for left hand is simple and easy to use inline with most of Logi mouses. It’s key attributes are: - Made for large sized left hands; - SmartWheel - Silent Clicks - Customizable Side Buttons - Comfort and upgraded for long hours - Connect via Bluetooth or with included Logi Bolt USB Receiver - Comes in smaller size. Upon unpacking and connecting to MacBook or Windows machines were straight and simple. It need to go through regular setting to customize to adjust to personal preferences. In this aspect it doesn’t require or have any differences with existing models. I have used the smart wheel and silent clicks mostly. And the silent click was most remarkable way of using compared to previous or other models. As click doesn’t feel that plastic touching noise that we are used. As click, works perfectly but smooth almost like something is missing but in the same time glad it is the way. It is battery based charging and according to the manufacturer claim should last 24 Months. But naturally will vary one length of personal usage.
This review is from Logitech - Signature M650 L Wireless Left-Handed Scroll Mouse with Silent Clicks - Wireless - Graphite
Posted by MigDigital