A:Answer I don't remember what the maximum capacity of Windows Vista is but I know that it is less than 8TB, I think it was 4TB, but can't remember for sure that has been so long ago. Another item worth noting is that chances are pretty high that the Western Digital software won't work as well. Additionally it is worth noting that Windows Vista also doesn't support USB3.0 so you'll be stuck to USB2.0 speeds, (480 megabits) which is quite slow, especially when you're looking at filling this large of a volume, in the perfect lab conditions, it would take over 42 hours to transfer 8TB, however, in real world circumstances it would take double that time, now couple that you're dealing with really old hardware so your speed will be impaired even more, I would not recommend this hard drive for use with Windows Vista